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Showing posts from January, 2021

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When public refer to contemporary medicine, accuracy plays one of the most important roles and people’s lives are directly dependent on it. Likewise, any researches pertaining to medicine are required to meet the highest standards. The issue nowadays is that any conclusions of researches can be posted online and used as a reference without being properly verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and tried to develop an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality indicator. That assists both readers and authors to quality-check publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with corresponding scores higher tha

Estrogen Receptor Polymorphism Linked to Dementia in Brazilian Cohort

In an effort to learn more about dementia, researchers evaluated 178 elderly Brazilian participants in a study on estrogen receptor polymorphisms. oncotarget journal impact factor Amyloid plaques forming between neurons. Beta-amyloid protein disrupting nerve cells function in a brain with Alzheimer’s disease Listen to an audio version of this article Dementia is used as a general term to describe the age-related decline in mental capabilities that are severe enough to interfere with day-to-day activities. This disorder is multifactorial and stems from genetic, metabolic, and environmental interactions. In the elderly, Alzheimer’s disease is the most common cause of dementia. As we continue to live longer, statistics have shown that the world’s elderly population is quickly increasing. Becoming elderly often coincides with a change in lifestyle, occupation, and income—which can contribute to the onset of dementia and other chronic-degenerative diseases. The conditions that affect th

clinics in us

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When general population speak of today’s medicine, precision plays one of the most significant roles and human lives are literally dependent on it. Hence, any researches related to medicine are required to comply with the highest standards. The issue today is that any results of researches can be published online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and decided to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality indicator. That allows both readers and authors to validate publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores hi

Estrogen Receptor Polymorphism Linked to Dementia in Brazilian Cohort

In an effort to learn more about dementia, researchers evaluated 178 elderly Brazilian participants in a study on estrogen receptor polymorphisms. Oncotarget website Amyloid plaques forming between neurons. Beta-amyloid protein disrupting nerve cells function in a brain with Alzheimer's disease Amyloid plaques forming between neurons. Beta-amyloid protein disrupting nerve cells function in a brain with Alzheimer’s disease Listen to an audio version of this article Dementia is used as a general term to describe the age-related decline in mental capabilities that are severe enough to interfere with day-to-day activities. This disorder is multifactorial and stems from genetic, metabolic, and environmental interactions. In the elderly, Alzheimer’s disease is the most common cause of dementia. As we continue to live longer, statistics have shown that the world’s elderly population is quickly increasing. Becoming elderly often coincides with a change in lifestyle, occupation, and inco

us clinics lists

Image
When public refer to contemporary medicine, precision plays one of the most crucial roles and people’s lives are directly dependent on it. Hereby, any researches related to medicine are necessary to comply with the top standards. The problem today is that any outcomes of researches can be published online and used as a reference without being adequately verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this issue and decided to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality indicator. That helps both readers and authors to validate publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores above 100 as

hospitals in us

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When general population discuss contemporary medicine, precision plays one of the most important roles and human lives are directly dependent on it. Likewise, any researches related to medicine are required to meet the top standards. The issue today is that any recommendations of researches can be published online and used as a reference without being adequately verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and attempted to create an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality indicator. That helps both readers and authors to validate publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores above

Trending with Impact: Melatonin’s Anticancer Effect in Prostate Cancer

A retrospective study from Russia demonstrates the anticancer effects of melatonin in poor-prognosis prostate cancer patients after combined hormone radiation treatment. San Antonio hospitals The Trending with Impact series highlights Oncotarget publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. — oncotarget impact factor Listen to an audio version of this article The pineal gland is located in the center of the brain and, through cues from our environment, secretes a naturally occurring hormone: melatonin. Melatonin is responsible for maintaining and regulating the body’s circadian rhythm. It is also widely-known as a dietary supplement that can be purchased in synthetic forms to aid in improving sleep and insomnia. However, for the past few

hospitals in us

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When general population refer to modern medicine, accuracy plays one of the most significant roles and people’s lives are directly dependent on it. Hence, any researches related to medicine are required to meet the highest standards. The challenge nowadays is that any results of researches can be shared online and used as a reference without being properly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this issue and decided to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality measure. That helps both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with respective scores higher th

Behind the Study: Secretomes in Breast Cancer Cells Induce MSC Actions

Researchers describe their paper published in Oncotarget titled, “Secretomes from metastatic breast cancer cells, enriched for a prognostically unfavorable LCN2 axis, induce anti-inflammatory MSC actions and a tumor-supportive premetastatic lung.” Behind The Study Researchers explain their studies that were published in Oncotarget The Behind the Study series transcribes videos of chosen researchers elaborating on their recent papers published in Oncotarget. Visit the Oncotarget YouTube channel for more insights from outstanding authors. oncotarget journal impact factor Jonathan Kelber Hello. I’m Jonathan Kelber, and I’m a associate professor at Cal State Northridge in the Los Angeles area. I’m currently on my sabbatical leave from there as a Fulbright Cancer Research UK Scholar at the University of Manchester. And today my grad student Francesca and I will be telling you a little bit about our work on our recent publication in Oncotarget titled “Secretomes from Metastatic Breas

hospitals in us

Image
When general population discuss contemporary medicine, accuracy plays one of the most important roles and people’s lives are directly dependent on it. Hence, any researches pertaining to medicine are necessary to comply with the top standards. The problem today is that any results of researches can be published online and used as a reference without being properly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality indicator. That allows both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores abo

us clinics lists

Image
When public mention modern medicine, accuracy plays one of the most significant roles and people’s lives are literally dependent on it. Hereby, any researches related to medicine are necessary to comply with the top standards. The issue nowadays is that any results of researches can be posted online and used as a reference without being properly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and tried to create an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality indicator. That helps both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with corresponding scores higher than 100 as

Structured Physical Exercise Reveals Anticancer Biomarkers

For the first time, microRNA biomarkers were found proving a direct correlation between a reduced rate of cancer and structured physical activity. Oncotarget journal Regular exercise doesn’t merely burn fat and build muscle to maintain a show-stopping physique. According to the World Health Organization, the lack of structured physical activity is a main risk factor in the diagnosis of breast and colon cancer, diabetes, and ischemic heart disease. In addition, at least two hours per week of structured physical activity has been found to significantly improve the prognosis for those already diagnosed with breast cancer. A recent paper published in Oncotarget – a premier open-access scientific journal – details an important study identifying the particular mechanisms involved in producing the now scientifically proven anticancer benefits of structured physical activity. The team chose to study the mechanisms responsible for the anticancer effects shown by structured physical exercise

clinics in us

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When general population speak of modern medicine, accuracy plays one of the most significant roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are required to meet the highest standards. The issue today is that any conclusions of researches can be shared online and used as a reference without being properly verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That assists both readers and authors to quality-check publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with corresponding scores

Hypoxic Exosomes Enhance Ewing’s Sarcoma Cells

Researchers in this study demonstrate that oxygen deprived Ewing’s sarcoma cells release exosomes, which transmit signals to enhance tumor survival. 3D render of exosomes ADN vesicles 3D render of exosomes ADN vesicles A recent study was published in Oncotarget about Ewing’s sarcoma (EWS) and performed by researchers from the University of Nebraska Medical Center and Creighton University – both located in Omaha, Nebraska, USA. Ewing’s sarcoma is a bone tumor that develops in children and adolescents. Treatment for this aggressive and highly malignant pediatric disease can be very successful in the early stages. However, patients that reach the later stages of EWS may only have a five-year survival rate of 25% or less. These poor outcomes are partly related to drug-resistant, stem-like cancer cells. The researchers demonstrate that hypoxic (oxygen deprived) EWS cells release exosomes, which are the mechanisms that enhance tumor survival by promoting stem-like characteristics within t

us clinics lists

Image
When general population discuss today’s medicine, precision plays one of the most important roles and people’s lives are directly dependent on it. Hereby, any researches related to medicine are necessary to meet the top standards. The issue nowadays is that any results of researches can be posted online and used as a reference without being thoroughly checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this issue and attempted to come up with an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to validate publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a complete publications list with corresponding scores higher than 10

us hospitals lists

Image
When public refer to contemporary medicine, precision plays one of the most significant roles and human lives are literally dependent on it. Hereby, any researches related to medicine are necessary to meet the highest standards. The problem nowadays is that any recommendations of researches can be published online and used as a reference without being adequately verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to generate an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That helps both readers and authors to quality-check publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with corresponding scor

Trending with Impact: HIV Drug Repurposed to Treat Lung Cancer

Researchers based out of South Africa published a new study of a drug most commonly used to treat HIV/AIDS, efavirenz, in an initial in vitro study to treat lung cancer. Untreated human lung cancer cell A549. Untreated human lung cancer cell A549. The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media — beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. — Efavirenz (EFV) is a non-nucleoside reverse transcriptase inhibitor drug commonly used for patients in the treatment of HIV/AIDS. Previous studies have shown that EFV also has cytotoxic effects against other cancer cells, such as colorectal, glioblastoma, and pancreatic. Researchers based out of South Africa published a new study in Oncotarget about EFV in the treatment of lung cancer and observed that numerous genes related to the cell cycle

hospitals in us

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When people mention contemporary medicine, precision plays one of the most crucial roles and people’s lives are directly dependent on it. Hereby, any researches pertaining to medicine are required to meet the highest standards. The problem nowadays is that any results of researches can be published online and used as a reference without being thoroughly verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and decided to develop an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality indicator. That assists both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a full publications list with respective scores higher than 100

Trending with Impact: Basal Cell Bladder Cancer and MEK Inhibitors

For patients with basal cell bladder cancer, researchers in this study identify MEK inhibitors as a viable therapeutic option. 3d Illustration - Bladder cancer cells 3d Illustration – Bladder cancer cell The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. — “Basal bladder cancer is frequently clinically aggressive and has the worst overall prognosis [3], and thus, additional therapeutic options for these tumors would be highly clinically relevant.” In this paper published by Oncotarget, researchers from the University of Michigan conducted a study emphasizing the importance of 3D culture screenings versus 2D, and the use of MEK inhibitors to target basal cell bladder cancer. This paper concludes that basal cell bladder cancer cells are sig

hospitals in us

Image
When people speak of contemporary medicine, precision plays one of the most significant roles and people’s lives are literally dependent on it. Hence, any researches pertaining to medicine are required to comply with the highest standards. The challenge today is that any recommendations of researches can be posted online and used as a reference without being adequately verified and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and decided to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with corre